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Tricaine-S (MS 222) Fish Anesthetic

17 reviews TRIC-M-GR-0010


Regular price $58.00


***2021 update: Tricaine now has a 12-mo expiration date from the time of manufacture. To ensure you receive the freshest batch possibly available, we will have your order shipped directly from the manufacturer to your door! 

Syndel's Tricaine-S (MS-222, TMS, tricaine methanesulfonate) is an FDA approved fish anesthetic (FDA ANADA 200-226) used for the temporary immobilization of fish, amphibians, and other aquatic cold-blooded animals (poikilotherms). Tricaine-S has long been recognized as a valuable tool for the proper handling of these animals during manual spawning (fish stripping), weighing, measuring, marking, surgical operations, transport, photography, and research.

Syndel is the world's largest manufacturer of Tricaine-S. It is made in FDA inspected Ferndale, Washington USA manufacturing plant according to Good Manufacturing Practices (GMP) and Good Laboratory Practices (GLP), which ensures the purity, strength, and quality of the product.

Tricaine-S (MS-222) is a fine crystalline powder fish anesthetic that is mixed with water prior to use. MS-222 is safe and effective for the anesthesia of fish when used as directed.

Commonly also sold under the name of Finquel.

The American Fisheries Society - Fish Culture Section's Working Group on Aquaculture Drugs, Chemicals, and Biologics (WGADCB) has published a Guide to Using Drugs, Biologics and Other Chemicals in Aquaculture. WGADCB have also developed a Treatment Calculator to assist in the dosage calculations of certain products.

Tricaine-S is a USFDA registered drug of Western Chemical Inc. a subsidiary of Aquatic Life Sciences, Inc.

Product Downloads

Tricaine-S - Directions for Use (PDF Size: 222.5 KB)
Tricaine-S - Dosage Chart (PDF Size: 43.2 KB)
Tricaine-S SDS (PDF Size: 237.2 KB)


If sedating for spawning, try Ovaprim.

Customer Reviews
4.8 Based on 17 Reviews
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Ronald K.
United States United States
Easy Purchase

We haven't officially received the product yet, but it's out for delivery. Assuming it is what we ordered, all is well. Play it Koi was good to work with me to cancel and reorder after my mistake. Thanks for good customer service.

United States United States
Short expiration date

The product is good and customer service is awesome. I do dislike the fact that this product has such a short expiration date.

United States United States
Excellent customer service, great product

We needed to move one large indoor aquarium fish to an observation/hospital tank and move several other outside fish from one pond to another. To reduce the chance of injury to the fish during the moves, we consulted with some of our field biologist friends and they suggested Tricaine-S (MS 222) fish anesthetic. We found several sources, but chose to do business with Ben and PlayItKoi based on the web site information related to the Tricaine-S application method and dosage, product availability, and positive reviews. The order was processed accurately, the shipment was fast, the contents were packed securely, and the Tricaine-S was factory sealed, fresh, and in-date. Ben followed up quickly and courteously to an email from us and wished us good luck with our tasks. All went very well. We look forward to ordering other items from Ben and PlayItKoi.

Marion d.
United States United States
Great transaction

Good product, arrived very quickly in the perfect size package, no excess waste. Made process very easy

United States United States
Great service

Quick service and no problems